NOW AVAILABLE:
COST-EFFECTIVE SERVICE CRYSTALLOGRAPHY
at the Australian Synchrotron
WHY CHOOSE US?
>> Highly competitive commercial rates - contact us for quotation
>> State-of-the-art 3rd generation synchrotron MX beamlines with demonstrated results
>> Expert beamline team, highly skilled in diffraction data collection and structure determination
>> Experimentally-verified test data providing daily calibration benchmarks and ISO certification
WHAT DO WE OFFER?
• Service crystallography - just send your samples!
• Remote use with access to all beamline functions including sample mounting, data collection and MAD scans
• Robot and software automation, key to delivering fast, reliable and easy-to-access results
• Two beamlines dedicated to both macromolecular & chemical crystallography
• MX1 beamline that is highly suited to fragment-based drug design with 50 datasets from >100 crystals typically screened over a 24hr period
• MX2 micro-focus beamline for determination of challenging structures including crystals from viral and membrane proteins
TECHNICAL CAPABILITIES: WHAT YOU NEED TO KNOW
| MX1 | MX2 |
| High-throughput beamline using a bending magnet source |
Micro crystallography beamline using an undulator source
|
| Beam size at the sample of 150 x 120μm (FWHM, HxV) | Micro focus beam at the sample of 30 x 20μm (FWHM, HxV) |
| Flux at the sample of 1.35 x 1011 photons per second (13.0keV) | Flux at the sample of 4.0 x 1012 photons per second (12.6keV) |
| Ideal for crystalline samples of >100μm or other highly-diffracting samples not requiring the flux of an undulator beam | Ideal for crystalline samples of <100μm or other poorly-diffracting samples requiring the additional available flux |
| User-changeable energy: 9.0keV (1.38Å) to 17.5keV (0.71Å) | Beams of 20 x 20μm and 10 x 10μm available using a micro collimator |
| User-changeable energy: 9.0keV (1.38Å) to 15.5keV (0.80Å) | |
| Automatic data reduction using XDS and automatic structure solution with AutoRickshaw | |
| Stanford BluICE beamline control GUI | |
| Temperature control at the sample position between 100 - 400K | |
| SAM-style sample-loading robot that accepts both SSRL cassettes and unipuck pin holders | |
| Room temperature tray screening capabilities to enable crystal evaluation in situ | |
| Real-time data indexing, strategy and analysis, facilitating optimal experiments | |
| Active steering of the beam to the sample position | |
| Customised solutions and enhanced capabilities are offered by our specialist beamline team | |
FOR MORE INFORMATION, CONTACT US AT
commercial@synchrotron.org.au
+61 3 8540 4232